BDBM764880 2-butyl-7-(hexahydropyridin-4-yl)-1-(3,4,5,6-tetrahydro-2H-pyran-4-ylmethyl)thieno[3,2-b]imidazo[4,5-d]pyridine-4-amine ::US20250257071, Compound 33

SMILES CCCCc1nc2c(N)nc3cc(C4CCNCC4)sc3c2n1CC1CCOCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 764880   

TargetToll-like receptor 7(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM764880(2-butyl-7-(hexahydropyridin-4-yl)-1-(3,4,5,6-tetra...)
Affinity DataEC50:  30nMAssay Description:1. HEK-Blue hTLR7 cells (Invivogen) were cultured in DMEM medium (Hyclone) containing 10% FBS heat-inactivated fetal bovine serum (Corning). On the d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM764880(2-butyl-7-(hexahydropyridin-4-yl)-1-(3,4,5,6-tetra...)
Affinity DataEC50:  1.89E+4nMAssay Description:1. HEK-Blue hTLR8 cells (Invivogen) were cultured in DMEM medium (Hyclone) containing 10% FBS heat-inactivated fetal bovine serum (Corning). On the d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent