BDBM764934 N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(trans-3-(cis-2,6-dimethylmorpholinyl)cyclobutoxy)-3-(ethyl(tetrahydrofuran-3-yl)amino)-2-methylbenzamide::US12390472, Example 46

SMILES CCN(c1cc(O[C@H]2C[C@H](N3C[C@@H](C)O[C@@H](C)C3)C2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 764934   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764934(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent