BDBM765056 4-((1-(cyclopropylcarbamoyl)indolin-5-yl)oxy)-7-methoxyquinoline-6-carboxamide::US12391666, Compound 1

SMILES COc1cc2nccc(Oc3ccc4c(c3)CCN4C(=O)NC3CC3)c2cc1C(N)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 765056   

TargetVascular endothelial growth factor receptor 2(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM765056(4-((1-(cyclopropylcarbamoyl)indolin-5-yl)oxy)-7-me...)
Affinity DataIC50: 10nMAssay Description:The in vitro activity of VEGFR2 was determined by detecting the phosphorylation level of the substrate in the kinase reaction using a homogeneous tim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 3(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM765056(4-((1-(cyclopropylcarbamoyl)indolin-5-yl)oxy)-7-me...)
Affinity DataIC50: 10nMAssay Description:The in vitro activity of VEGFR3 was determined by detecting the phosphorylation level of the substrate in the kinase reaction using a HTRF kinase det...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 1(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM765056(4-((1-(cyclopropylcarbamoyl)indolin-5-yl)oxy)-7-me...)
Affinity DataIC50: 55nMAssay Description:The in vitro activity of VEGFR1 was determined by detecting the phosphorylation level of the substrate in the kinase reaction using a homogeneous tim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent