BDBM765078 US12391669, Compound 20

SMILES Cc1ccc(C(=O)NCc2ccccc2Cl)cc1Oc1ncsc1-c1ccnc(N[C@H]2CCCNC2)n1

InChI Key InChIKey=IGMBOIUWHDALPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 765078   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
University Of California

US Patent
LigandChemical structure of BindingDB Monomer ID 765078BDBM765078(US12391669, Compound 20)
Affinity DataIC50: 52nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE2(Human)
University Of California

US Patent
LigandChemical structure of BindingDB Monomer ID 765078BDBM765078(US12391669, Compound 20)
Affinity DataIC50: 1.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent