BDBM765086 6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,4-triazin-3-amine::US12391670, Example 1

SMILES Fc1cnccc1-c1nnc(Nc2cccnc2)nc1-c1cccnc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 765086   

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765086(6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,...)
Affinity DataKi:  282nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765086(6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,...)
Affinity DataIC50: 320nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Leadxpro

US Patent
LigandPNGBDBM765086(6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,...)
Affinity DataKi:  9.55E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM765086(6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,...)
Affinity DataIC50: 1.85E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM765086(6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,...)
Affinity DataKi:  1.86E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Leadxpro

US Patent
LigandPNGBDBM765086(6-(3-fluoropyridin-4-yl)-N,5-di(pyridin-3-yl)-1,2,...)
Affinity DataIC50: 1.90E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent