BDBM765093 5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluoromethyl)pyridin-4-yl)-1,2,4-triazin-3-amine::US12391670, Example 8

SMILES Fc1ccccc1-c1nc(Nc2cccnc2)nnc1-c1ccnc(C(F)(F)F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 765093   

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765093(5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluor...)
Affinity DataKi:  224nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765093(5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluor...)
Affinity DataIC50: 250nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Leadxpro

US Patent
LigandPNGBDBM765093(5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluor...)
Affinity DataKi:  1.02E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Leadxpro

US Patent
LigandPNGBDBM765093(5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluor...)
Affinity DataIC50: 1.35E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM765093(5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluor...)
Affinity DataKi:  2.40E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM765093(5-(2-fluorophenyl)-N-(pyridin-3-yl)-6-(2-(trifluor...)
Affinity DataIC50: 2.41E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent