BDBM765096 N-(5-(2-fluorophenyl)-6-(2-(trifluoromethyl)pyridin-4-yl)-1,2,4-triazin-3-yl)-3-methyl-1,2,4-thiadiazol-5-amine::US12391670, Example 11

SMILES Cc1nsc(Nc2nnc(-c3ccnc(C(F)(F)F)c3)c(-c3ccccc3F)n2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 765096   

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765096(N-(5-(2-fluorophenyl)-6-(2-(trifluoromethyl)pyridi...)
Affinity DataKi:  891nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765096(N-(5-(2-fluorophenyl)-6-(2-(trifluoromethyl)pyridi...)
Affinity DataIC50: 1.01E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM765096(N-(5-(2-fluorophenyl)-6-(2-(trifluoromethyl)pyridi...)
Affinity DataKi: >2.00E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent