BDBM765101 1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2,4-triazin-3-yl)-3-methylurea::US12391670, Example 16

SMILES CNC(=O)Nc1nnc(-c2ccncc2F)c(-c2ccccc2F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 765101   

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataKi:  145nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataIC50: 160nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataKi:  1.86E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataIC50: 3.79E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataKi:  7.24E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataIC50: 9.52E+3nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM765101(1-(5-(2-fluorophenyl)-6-(3-fluoropyridin-4-yl)-1,2...)
Affinity DataKi: >2.00E+4nMAssay Description:For all four adenosine receptors (A1, A2A, A2B and A3) filtration binding assay was performed. Radioligand binding competition assay was done in dupl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent