BDBM765174 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile ::US12391677, Compound MGL-3196

SMILES CC(C)c1cc(OC2C(Cl)=CC(n3nc(C#N)c(=O)[nH]c3=O)=CC2Cl)n[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 765174   

TargetThyroid hormone receptor beta(Human)
Inventisbio

US Patent
LigandPNGBDBM765174(2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropy...)
Affinity DataEC50:  300nMAssay Description:The ligand binding domain of thyroid hormone receptor alpha and the ligand binding domain of thyroid hormone receptor beta with GST tag were purchase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
Inventisbio

US Patent
LigandPNGBDBM765174(2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropy...)
Affinity DataEC50:  3.24E+3nMAssay Description:The ligand binding domain of thyroid hormone receptor alpha and the ligand binding domain of thyroid hormone receptor beta with GST tag were purchase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent