BDBM765365 5-(1-(2,2-difluoroethyl)-1H-pyrazol-3-yl)-3-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl)-1H-pyrazolo[3,4-b]pyridine::US12391687, Example 36
SMILES Fc1ccc(F)c([C@H]2C[C@H](F)CN2c2n[nH]c3ncc(-c4ccn(CC(F)F)n4)cc23)c1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 765365
Affinity DataIC50: 1nMAssay Description:Table 1: Experimental MethodThe tested compounds were subjected to 3-fold serial dilution to reach a final concentration of 1 μM to 0.05 nM (10 conce...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Table 1: Experimental MethodThe tested compounds were subjected to 3-fold serial dilution to reach a final concentration of 1 μM to 0.05 nM (10 conce...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Table 1: Experimental MethodThe tested compounds were subjected to 3-fold serial dilution to reach a final concentration of 1 μM to 0.05 nM (10 conce...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor [G595R](Human)
Shanghai Ennovabio Pharmaceuticals
US Patent
Shanghai Ennovabio Pharmaceuticals
US Patent
Affinity DataIC50: 1nMAssay Description:Table 3: Experimental MaterialsThe recombinant human TRKA (G595R), TRKA (G667C) and TRKC (G623R) proteins were purchased from SignalChem. HTRF kinEAS...More data for this Ligand-Target Pair