BDBM765366 2-(3-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)-5-(methoxymethyl)-1,3,4-oxadiazole::US12391687, Example 37

SMILES COCC1=NNC(c2cnc3[nH]nc(N4C[C@@H](F)C[C@@H]4c4cc(F)ccc4F)c3c2)O1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 765366   

LigandPNGBDBM765366(2-(3-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrro...)
Affinity DataIC50: 1nMAssay Description:Table 1: Experimental MethodThe tested compounds were subjected to 3-fold serial dilution to reach a final concentration of 1 μM to 0.05 nM (10 conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM765366(2-(3-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrro...)
Affinity DataIC50: 1nMAssay Description:Table 1: Experimental MethodThe tested compounds were subjected to 3-fold serial dilution to reach a final concentration of 1 μM to 0.05 nM (10 conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM765366(2-(3-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrro...)
Affinity DataIC50: 1nMAssay Description:Table 3: Experimental MaterialsThe recombinant human TRKA (G595R), TRKA (G667C) and TRKC (G623R) proteins were purchased from SignalChem. HTRF kinEAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM765366(2-(3-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrro...)
Affinity DataIC50: 1nMAssay Description:Table 1: Experimental MethodThe tested compounds were subjected to 3-fold serial dilution to reach a final concentration of 1 μM to 0.05 nM (10 conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent