BDBM766048 US20250263423, Example 4

SMILES C#Cc1cccc2cc(O)cc(-c3ncc4c(C5CC6COCC(C5)N6)nc(OCC56CCCN5CCC6)nc4c3F)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 766048   

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Bridgene Biosciences

US Patent
LigandPNGBDBM766048(US20250263423, Example 4)
Affinity DataIC50: 10nMAssay Description:A HTRF-based nucleotide exchange assay is used to characterize the pharmacological properties of the synthesized inhibitor compounds and the IC50 mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/3/2025
Entry Details
US Patent