BDBM766228 9-(3-(methoxymethyl)bicyclo[1.1.1]pentan-1-yl)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one ::US20250263753, Compound 20
SMILES COCC12CC(n3c(=O)n(C)c4cnc(Nc5cn6ncnc6cc5C)nc43)(C1)C2
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 766228
Affinity DataIC50: 5.5nMAssay Description:The assay detects kinase activity by antibody based HTRF assay. The GST-tagged p53 protein serves as substrate and Eu-labeled-antibody with specific ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.01% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO Required ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Juno Therapeutics
US Patent
Juno Therapeutics
US Patent
Affinity DataIC50: 550nMAssay Description:A solution was prepared containing 0.2 nM Anti-HIS-Terbium (Cisbio, 64CUSTAZU), 3.7 nM designed-probe and 1.0 nM His-PIK3CA/PIK3R1 (p110 alpha/p85 al...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Juno Therapeutics
US Patent
Juno Therapeutics
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti-HIS-Terbium (Cisbio, 64CUSTAZU), 40 nM designed-probe and 1.0 nM His-PIK3CD/PIK3R1 (p110 delta/p85 alp...More data for this Ligand-Target Pair