BDBM766373 Ent-5-Chloro-N-{[4-(5-Methyl-1,3-Thiazol-4-Yl)-2,5-Dioxoimidazolidin-4-Yl]Methyl}-4''-(Trifluoromethyl)[Biphenyl]-2-Carboxamide::US12398120, Example 16

SMILES Cc1scnc1C1(CNC(=O)c2ccc(Cl)cc2-c2ccc(C(F)(F)F)cc2)NC(=O)NC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766373   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766373(Ent-5-Chloro-N-{[4-(5-Methyl-1,3-Thiazol-4-Yl)-2,5...)
Affinity DataIC50: 4.15nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766373(Ent-5-Chloro-N-{[4-(5-Methyl-1,3-Thiazol-4-Yl)-2,5...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent