BDBM766498 4''-(2,2-Difluorocyclopropyl)-4,5-Difluoro-N-{[4-(1-Methyl-1H-Imidazol-2-Yl)-2,5-Dioxoimidazolidin-4-Yl]Methyl}[1,1''-Biphenyl]-2-Carboxamide (Mixture of Diastereoisomers)::US12398120, Example 143

SMILES Cn1ccnc1C1(CNC(=O)c2cc(F)c(F)cc2-c2ccc(C3CC3(F)F)cc2)NC(=O)NC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766498   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766498(4'-(2,2-Difluorocyclopropyl)-4,5-Difluoro-N-{[4-(1...)
Affinity DataIC50: 5.60nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766498(4'-(2,2-Difluorocyclopropyl)-4,5-Difluoro-N-{[4-(1...)
Affinity DataIC50: 4.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent