BDBM766508 Ent-5-Chloro-4''-Methyl-N-{[4-(1-Methyl-1H-Imidazol-2-Yl)-2,5-Dioxoimidazolidin-4-Yl]Methyl}[Biphenyl]-2-Carboxamide::US12398120, Example 153

SMILES Cc1ccc(-c2cc(Cl)ccc2C(=O)NCC2(c3nccn3C)NC(=O)NC2=O)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766508   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766508(Ent-5-Chloro-4'-Methyl-N-{[4-(1-Methyl-1H-Imidazol...)
Affinity DataIC50: 2.40nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766508(Ent-5-Chloro-4'-Methyl-N-{[4-(1-Methyl-1H-Imidazol...)
Affinity DataIC50: 510nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent