BDBM766543 Ent-5-Chloro-N-{[4-(1-Methyl-1H-Pyrazol-5-Yl)-2,5-Dioxoimidazolidin-4-Yl]Methyl}-4''-(Trifluoromethyl)[Biphenyl]-2-Carboxamide::US12398120, Example 188

SMILES Cn1nccc1C1(CNC(=O)c2ccc(Cl)cc2-c2ccc(C(F)(F)F)cc2)NC(=O)NC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766543   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766543(Ent-5-Chloro-N-{[4-(1-Methyl-1H-Pyrazol-5-Yl)-2,5-...)
Affinity DataIC50: 5.27nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766543(Ent-5-Chloro-N-{[4-(1-Methyl-1H-Pyrazol-5-Yl)-2,5-...)
Affinity DataIC50: 2.73E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent