BDBM766569 Ent-5,6-Difluoro-N-[(4-Isopropyl-2,5-Dioxoimidazolidin-4-Yl)Methyl]-4''-(Trifluoromethyl)[Biphenyl]-2-Carboxamide::US12398120, Example 214

SMILES CC(C)C1(CNC(=O)c2ccc(F)c(F)c2-c2ccc(C(F)(F)F)cc2)NC(=O)NC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766569   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766569(Ent-5,6-Difluoro-N-[(4-Isopropyl-2,5-Dioxoimidazol...)
Affinity DataIC50: 8.97nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766569(Ent-5,6-Difluoro-N-[(4-Isopropyl-2,5-Dioxoimidazol...)
Affinity DataIC50: 3.75E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent