BDBM766633 Ent-N-{[2,5-Dioxo-4-(1,3-Thiazol-4-Yl)Imidazolidin-4-Yl]Methyl}-5,6-Difluoro-4''-(Trifluoromethyl)[Biphenyl]-2-Carboxamide::US12398120, Example 278

SMILES O=C1NC(=O)C(CNC(=O)c2ccc(F)c(F)c2-c2ccc(C(F)(F)F)cc2)(c2cscn2)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766633   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766633(Ent-N-{[2,5-Dioxo-4-(1,3-Thiazol-4-Yl)Imidazolidin...)
Affinity DataIC50: 3.65nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM766633(Ent-N-{[2,5-Dioxo-4-(1,3-Thiazol-4-Yl)Imidazolidin...)
Affinity DataIC50: 8.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent