BDBM766785 US12398153, Compound WX001B

SMILES Cc1cccc(CN2C(=O)c3nc(-c4ccnc(Nc5ccnn5C)n4)sc3[C@]23CCOC3)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 766785   

TargetMitogen-activated protein kinase 1(Human)
D3 Bio (Wuxi) Co.

US Patent
LigandPNGBDBM766785(US12398153, Compound WX001B)
Affinity DataIC50: 0.320nMAssay Description:1. Purpose of the Assay:The ability of compounds to inhibit ERK2 kinase activity was measured.2. Assay Buffer:20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent