BDBM766788 US12398153, Compound WX004

SMILES Cn1nccc1Nc1nccc(-c2nc3c(s2)C2(COC2)N(Cc2cccc(F)c2)C3=O)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 766788   

TargetMitogen-activated protein kinase 1(Human)
D3 Bio (Wuxi) Co.

US Patent
LigandPNGBDBM766788(US12398153, Compound WX004)
Affinity DataIC50: 1.10nMAssay Description:1. Purpose of the Assay:The ability of compounds to inhibit ERK2 kinase activity was measured.2. Assay Buffer:20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent