BDBM766818 US20250268854, Example 30

SMILES COc1cc(Cl)cc(CN[C@@H](CCC(C)(C)C)C(=O)O)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766818   

TargetSortilin(Human)
C/O Vesper Bio

US Patent
LigandPNGBDBM766818(US20250268854, Example 30)
Affinity DataKd:  450nMAssay Description:Compounds were screened at a final assay concentration of 1 μM and a final DMSO concentration was 1%. To achieve this, compounds were diluted in DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

TargetNeurotensin/neuromedin N(Human)
C/O Vesper Bio

US Patent
LigandPNGBDBM766818(US20250268854, Example 30)
Affinity DataIC50: 580nMAssay Description:Compound affinity was determined by measuring the displacement of [3H]-neurotensin binding to h-Sortilin in SPA format. Total volume of 40 μl in 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent