BDBM766900 (2S)-2-{[(5-methoxypyridin-3-yl)methyl]amino}-5,5-dimethylhexanoic acid::US20250268854, Example 144

SMILES COC1C=C(CN[C@@H](CCC(C)(C)C)C(=O)O)C=NC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766900   

TargetSortilin(Human)
C/O Vesper Bio

US Patent
LigandPNGBDBM766900((2S)-2-{[(5-methoxypyridin-3-yl)methyl]amino}-5,5-...)
Affinity DataKd:  310nMAssay Description:Compounds were screened at a final assay concentration of 1 μM and a final DMSO concentration was 1%. To achieve this, compounds were diluted in DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

TargetNeurotensin/neuromedin N(Human)
C/O Vesper Bio

US Patent
LigandPNGBDBM766900((2S)-2-{[(5-methoxypyridin-3-yl)methyl]amino}-5,5-...)
Affinity DataIC50: 430nMAssay Description:Compound affinity was determined by measuring the displacement of [3H]-neurotensin binding to h-Sortilin in SPA format. Total volume of 40 μl in 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent