BDBM766904 N-(5-(7''-Fluoro-3''-::US20250268873, Compound 570

SMILES CCS(=O)(=O)NC1=CC(C2=CC3C4=C(C=NC3CC2F)N(C)C(=O)C42CCC2)CN=C1OCCNC(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 766904   

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 0.630nMAssay Description:On day one, a 96-well plate (ThermoFisher, Cat #: 442404) was coated with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 21nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 55nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 100nMAssay Description:mTOR Kinase reactions were performed in a 10 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008260 plates were used. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent