BDBM767008 US20250268897, Compound 21

SMILES Cc1cc(Nc2cc(C)[nH]n2)nc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(-c4ccc[nH]4)nc3)nc2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 767008   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810S](Human)
Sichuan Kelun-Biotech Biopharmaceutical Co.

US Patent
LigandPNGBDBM767008(US20250268897, Compound 21)
Affinity DataIC50: 6.61nMAssay Description:The three drug-resistant mutant RET enzymes were each pre-incubated with different concentrations of test compounds (in the inhibition rate test of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810C](Human)
Sichuan Kelun-Biotech Biopharmaceutical Co.

US Patent
LigandPNGBDBM767008(US20250268897, Compound 21)
Affinity DataIC50: 173nMAssay Description:The three drug-resistant mutant RET enzymes were each pre-incubated with different concentrations of test compounds (in the inhibition rate test of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent