BDBM767011 Fumarate of 2-(4-fluoro-1-(5-((3-(5-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl) amino) pyrimidin-2-yl) pyridin-2-yl)-3,6-diazabicyclo [3.1.1] heptan-6-yl) methyl) pyridin-2-yl)-1H-pyrazol-3-yl) propan-2-ol ::US20250268897, Compound 30-A

SMILES Cc1cc(Nc2cc(C)[nH]n2)nc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(-n4cc(F)c(C(C)(C)O)n4)nc3)nc2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767011   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810C](Human)
Sichuan Kelun-Biotech Biopharmaceutical Co.

US Patent
LigandPNGBDBM767011(Fumarate of 2-(4-fluoro-1-(5-((3-(5-(4-methyl-6-((...)
Affinity DataIC50: 125nMAssay Description:The three drug-resistant mutant RET enzymes were each pre-incubated with different concentrations of test compounds (in the inhibition rate test of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent