BDBM767051 N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(pyrrolidin-1- yl)ethoxy)phenyl)-3-oxabicyclo[3.1.0]hexane-6-carboxamide::US20250270172, Compound 233

SMILES Cc1ncnc(C)c1-c1cc(NC(=O)C2(F)CC2)ccc1OCCN1CCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 767051   

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767051(N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(pyrrolidin...)
Affinity DataKi:  3.81nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767051(N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(pyrrolidin...)
Affinity DataKi:  4.66nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767051(N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(pyrrolidin...)
Affinity DataIC50: 8.55nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767051(N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(pyrrolidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767051(N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(pyrrolidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent