BDBM767105 N-[3-(4,6-dimethylpyrimidin-5-yl)-4-(2-pyrrolidin-1- ylethoxy)phenyl]-4-fluoro-2-methyl-pyrazole-3-carboxamide::US20250270172, Compound 290

SMILES Cc1ncnc(C)c1-c1cc(NC(=O)c2c(F)cnn2C)ccc1OCCN1CCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 767105   

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767105(N-[3-(4,6-dimethylpyrimidin-5-yl)-4-(2-pyrrolidin-...)
Affinity DataKi:  3.86nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767105(N-[3-(4,6-dimethylpyrimidin-5-yl)-4-(2-pyrrolidin-...)
Affinity DataIC50: 7.36nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767105(N-[3-(4,6-dimethylpyrimidin-5-yl)-4-(2-pyrrolidin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767105(N-[3-(4,6-dimethylpyrimidin-5-yl)-4-(2-pyrrolidin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent