BDBM767138 N-(4-(2-(azetidin-1-yl)ethoxy)-3-(4,6-dimethylpyrimidin-5-yl)phenyl)- 4-methylthiazole-5-carboxamide::US20250270172, Compound 306

SMILES Cc1ncsc1C(=O)Nc1ccc(OCCN2CCC2)c(-c2c(C)ncnc2C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 767138   

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767138(N-(4-(2-(azetidin-1-yl)ethoxy)-3-(4,6-dimethylpyri...)
Affinity DataKi:  2.65nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767138(N-(4-(2-(azetidin-1-yl)ethoxy)-3-(4,6-dimethylpyri...)
Affinity DataIC50: 6.14nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767138(N-(4-(2-(azetidin-1-yl)ethoxy)-3-(4,6-dimethylpyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent