BDBM767171 (R)-N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(3-methoxypyrrolidin-1- yl)ethoxy)phenyl)cyclopropanecarboxamide::US20250270172, Compound 353

SMILES CO[C@@H]4CCN(CCOc2ccc(NC(=O)C1CC1)cc2c3c(C)ncnc3C)C4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 767171   

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767171((R)-N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(3-meth...)
Affinity DataKi:  4.06nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767171((R)-N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(3-meth...)
Affinity DataIC50: 24.8nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767171((R)-N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(3-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM767171((R)-N-(3-(4,6-dimethylpyrimidin-5-yl)-4-(2-(3-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Radioligand binding assays were performed using [3H]5-HT as the radioligand using cell membranes prepared from HEK293 cells expressing recombinant 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent