BDBM767426 6-(6-(5-Chloro-2-fluorophenyl)-2,3- dihydro-1H-imidazo[1,2-a]imidazol- 5-yl)-[1,2,4]triazolo[1,5-a]pyridine::US20250270215, Example 2

SMILES Fc1ccc(Cl)cc1-c1nc2n(c1-c1ccc3ncnn3c1)CCN2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767426   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767426(6-(6-(5-Chloro-2-fluorophenyl)-2,3- dihydro-1H-imi...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent