BDBM767433 2-(6-(6-Chloropyridin-2-yl)-2,3- dihydro-1H-imidazo[1,2-a]imidazol- 5-yl)thieno[3,2-c]pyridine::US20250270215, Example 13

SMILES Clc1cccc(-c2nc3n(c2-c2cc4cnccc4s2)CCN3)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767433   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767433(2-(6-(6-Chloropyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent