BDBM767449 2-Fluoro-5-(6-(6-methylpyridin- 2-yl)-2,3-dihydro-1H- imidazo[1,2-a]imidazol-5- yl)aniline::US20250270215, Example 43

SMILES Cc1cccc(-c2nc3n(c2-c2ccc(F)c(N)c2)CCN3)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767449   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767449(2-Fluoro-5-(6-(6-methylpyridin- 2-yl)-2,3-dihydro-...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent