BDBM767450 6-(6-(6-Methylpyridin-2-yl)-2,3-dihydro-1H-imidazo[1,2-a]imidazol-5-yl)benzo[d] thiazol-2-amine::US20250270215, Example 48

SMILES Cc1cccc(-c2nc3n(c2-c2ccc4nc(N)sc4c2)CCN3)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767450   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767450(6-(6-(6-Methylpyridin-2-yl)-2,3-dihydro-1H-imidazo...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent