BDBM767581 2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[4,5-g]pyrano[3'',4'':6,7]indolizino[1,2-b]quinolin-14-yl)methyl)-2-hydroxyacetamide::US20250270227, Compound 14-P1

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)CC2=C(CNC(=O)[C@H](O)C3CC3)C3C=C4OCOC4=CC3N=C21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 767581   

TargetCytochrome P450 2C9(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM767581(2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo...)
Affinity DataIC50: 5.00E+4nMAssay Description:1. Preparation of 100 mM phosphate buffered saline (PBS): 7.098 g of Na2HPO4 was weighed, 500 mL of pure water was added and subjected to ultrasonic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM767581(2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo...)
Affinity DataIC50: 5.00E+4nMAssay Description:1. Preparation of 100 mM phosphate buffered saline (PBS): 7.098 g of Na2HPO4 was weighed, 500 mL of pure water was added and subjected to ultrasonic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM767581(2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo...)
Affinity DataIC50: 5.00E+4nMAssay Description:1. Preparation of 100 mM phosphate buffered saline (PBS): 7.098 g of Na2HPO4 was weighed, 500 mL of pure water was added and subjected to ultrasonic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent