BDBM767584 2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[4,5-g]pyrano[3'',4'':6,7]indolizino[1,2-b]quinolin-14-yl-2,2-d2)methyl)-2-hydroxyacetamide::US20250270227, Compound 39

SMILES [2H]C1([2H])OC2=CC3N=C4C(=C(CNC(=O)C(O)C5CC5)C3C=C2O1)Cn1c4cc2c(c1=O)COC(=O)[C@]2(O)CC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 767584   

TargetCytochrome P450 3A4(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM767584(2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo...)
Affinity DataIC50: 5.00E+4nMAssay Description:1. Preparation of 100 mM phosphate buffered saline (PBS): 7.098 g of Na2HPO4 was weighed, 500 mL of pure water was added and subjected to ultrasonic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM767584(2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo...)
Affinity DataIC50: 5.00E+4nMAssay Description:1. Preparation of 100 mM phosphate buffered saline (PBS): 7.098 g of Na2HPO4 was weighed, 500 mL of pure water was added and subjected to ultrasonic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM767584(2-cyclopropyl-N-(((S)-7-ethyl-7-hydroxy-8,11-dioxo...)
Affinity DataIC50: 5.00E+4nMAssay Description:1. Preparation of 100 mM phosphate buffered saline (PBS): 7.098 g of Na2HPO4 was weighed, 500 mL of pure water was added and subjected to ultrasonic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent