BDBM767586 US12403141, Example 1-D2

SMILES [2H]C([2H])(Oc1cc(C)n(-c2cc(-c3ccnc(C(C)(C)O)n3)ncc2C)c(=O)c1Cl)c1ncc(F)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767586   

TargetMitogen-activated protein kinase 14(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM767586(US12403141, Example 1-D2)
Affinity DataIC50: 10nMAssay Description:The novel, MK2 substrate-selective inhibitory mechanism of compounds is evaluated in enzyme assays comparing inhibitor potency in blocking p38/MK2 ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent