BDBM767649 6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,2,4- triazol-3-yl)-7-fluoro-5- methoxy-3-(1H-pyrazol-4-yl)- 1H-indole::US12404261, Example 65

SMILES COCC(F)(F)c1nnc(-c2[nH]c3c(F)c(Cl)c(OC)cc3c2-c2cn[nH]c2)[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767649   

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandPNGBDBM767649(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 31nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent