BDBM767674 6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,2,4- triazol-3-yl)-7-fluoro-3-(1H- imidazol-1-yl)-5-methoxy-1- methyl-1H-indole::US12404261, Example 89

SMILES COCC(F)(F)c1nnc(-c2c(-n3ccnc3)c3cc(OC)c(Cl)c(F)c3n2C)[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767674   

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandPNGBDBM767674(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 40nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent