BDBM767725 (1s,3s)-3-(3-amino-4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)-3-(cyanomethyl)cyclobutyl-1-carbonitrile::US12404275, Example 9

SMILES Cn1cc(-c2cn3nccc3c(-c3cn([C@]4(CC#N)C[C@H](C#N)C4)nc3N)n2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 767725   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767725((1s,3s)-3-(3-amino-4-(6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50: 0.170nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767725((1s,3s)-3-(3-amino-4-(6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50: 14nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent