BDBM767726 6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-4-trifluoromethanesulfonate ::US12404275, Example 10

SMILES Cn5cc(c4cn1nccc1c(c3cn([C@]2(CC#N)C[C@@H](C#N)C2)nc3N)n4)cn5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 767726   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767726(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin...)
Affinity DataIC50: 0.130nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767726(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin...)
Affinity DataIC50: 0.25nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent