BDBM767729 N-(1-((1r,3r)-3-cyano-1-(cyanomethyl)cyclobutyl)-4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-3-yl)acetamide::US12404275, Example 40

SMILES CC(=O)Nc1nn([C@]2(CC#N)C[C@@H](C#N)C2)cc1-c1nc(-c2cnn(C)c2)cn2nccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767729   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767729(N-(1-((1r,3r)-3-cyano-1-(cyanomethyl)cyclobutyl)-4...)
Affinity DataIC50: 139nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent