BDBM767736 (1r,3r)-3-(cyanomethyl)-3-(5-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclobutane-1-carbonitrile::US12404275, Example 50

SMILES Cn1cc(-c2cn3nccc3c(-c3cn([C@]4(CC#N)C[C@H](C#N)C4)c4ncncc34)n2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 767736   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767736((1r,3r)-3-(cyanomethyl)-3-(5-(6-(1-methyl-1H-pyraz...)
Affinity DataIC50: 0.410nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Primegene (Beijing) Co.

US Patent
LigandPNGBDBM767736((1r,3r)-3-(cyanomethyl)-3-(5-(6-(1-methyl-1H-pyraz...)
Affinity DataIC50: 10nMAssay Description:A compound (powder) was dissolved in 100% DMSO to prepare a 10 mM storage solution. The compound had an initial test concentration of 10,000 nM or 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent