BDBM768069 4-Hydroxy-4-((R)-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3-methoxy-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-2-yl)thio)(3-methylpyridin-2-yl)methyl)tetrahydro-2H-thiopyran1,1-dioxide::US12404295, Example 2.66.126R.I.

SMILES CO[C@@H]1[C@@H](n2cc(-c3cc(F)c(F)c(F)c3)nn2)[C@@H](O)[C@@H](CO)O[C@H]1S[C@H](c1ncccc1C)C1(O)CCS(=O)(=O)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 768069   

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768069(4-Hydroxy-4-((R)-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(h...)
Affinity DataIC50: 0.0900nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768069(4-Hydroxy-4-((R)-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(h...)
Affinity DataIC50: 60nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768069(4-Hydroxy-4-((R)-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(h...)
Affinity DataIC50: 60nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent