BDBM768410 (E)-4-(3- methoxypyrrolidin-1-yl)- 1-(4-(4-((3-methyl-4-((1- methyl-1H- benzo[d]imidazol-5- yl)oxy)phenyl)amino) pyrrolo[2,1-f][1,2,4]triazin- 5-yl)piperidin-1-yl)but-2- en-1-one::US20250276983, Example 106

SMILES COC1CCN(C/C=C/C(=O)N2CCC(c3ccn4ncnc(Nc5ccc(Oc6ccc7c(c6)ncn7C)c(C)c5)c34)CC2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 768410   

TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM768410((E)-4-(3- methoxypyrrolidin-1-yl)- 1-(4-(4-((3-met...)
Affinity DataIC50: 200nMAssay Description:The radioactive signal generated from the aliquot of buffer solution was proportional to the amount of radiolabeled substrate produced, and which is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM768410((E)-4-(3- methoxypyrrolidin-1-yl)- 1-(4-(4-((3-met...)
Affinity DataIC50: 200nMAssay Description:The radioactive signal generated from the aliquot of buffer solution was proportional to the amount of radiolabeled substrate produced, and which is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM768410((E)-4-(3- methoxypyrrolidin-1-yl)- 1-(4-(4-((3-met...)
Affinity DataIC50: 200nMAssay Description:The radioactive signal generated from the aliquot of buffer solution was proportional to the amount of radiolabeled substrate produced, and which is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent