BDBM768462 N-[(4S,5S)-6-ethoxy-4-(4- fluorophenyl)-3-methyl-1- phenyl-1H,4H,5H- pyrazolo[3,4-b]pyridin-5- yl]-3- (trifluoromethyl)benzamide::US12409171, Name RG-0009518

SMILES CCOC1=Nc2c(c(C)nn2-c2ccccc2)[C@H](c2ccc(F)cc2)[C@@H]1NC(=O)c1cccc(C(F)(F)F)c1

InChI Key InChIKey=JNSHYRAPQYBDAV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768462   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 768462BDBM768462(N-[(4S,5S)-6-ethoxy-4-(4- fluorophenyl)-3-methyl-1...)
Affinity DataEC50: >3.65E+4nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent