BDBM768545 N-{[(4S,5S)-7-ethyl-4-(4- fluorophenyl)-6-oxo-1- phenyl-5-[3- (trifluoromethyl) benzamido]- 1H,4H,5H,6H,7H- pyrazolo[3,4-b]pyridin-3- yl]methyl}-1-(5-{2-oxo- hexahydro-1H-thieno[3,4- d]imidazol-4- yl}pentanamido)-3,6,9,12- tetraoxapentadecan-15- amide::US12409171, Name RG-0014148

SMILES CCN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC3SCC4NC(=O)NC43)nn(-c3ccccc3)c21

InChI Key InChIKey=XNHQPLWELFKULE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768545   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 768545BDBM768545(N-{[(4S,5S)-7-ethyl-4-(4- fluorophenyl)-6-oxo-1- p...)
Affinity DataEC50:  102nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
12/17/2025
Entry Details
US Patent