BDBM768556 N-[(4S,5S)-3-({3-[2-(2-{5- [(3aS,4S,6aR)-2-oxo- hexahydro-1H-thieno[3,4- d]imidazol-4- yl]pentanamido}ethoxy) ethoxy]propanamido} methyl)-7- ethyl-4-(4-fluorophenyl)-6- oxo-1-phenyl- 1H,4H,5H,6H,7H- pyrazolo[3,4-b]pyridin-5- yl]-3- (trifluoromethyl)benzamide::US12409171, Name RG-0014159

SMILES CCN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(CNC(=O)CCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@@H]43)nn(-c3ccccc3)c21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768556   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandPNGBDBM768556(N-[(4S,5S)-3-({3-[2-(2-{5- [(3aS,4S,6aR)-2-oxo- he...)
Affinity DataEC50:  89.6nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent