BDBM768559 tert-butyl N-{2-[(4S,5S)-4- (4-fluorophenyl)-3-methyl- 6-oxo-1-phenyl-5-[3- (trifluoromethyl) benzamido]- 1H,4H,5H,6H,7H- pyrazolo[3,4-b]pyridin-7- yl]ethyl}carbamate::US12409171, Name RG-0014162

SMILES Cc1nn(-c2ccccc2)c2c1[C@H](c1ccc(F)cc1)[C@H](NC(=O)c1cccc(C(F)(F)F)c1)C(=O)N2CCNC(=O)OC(C)(C)C

InChI Key InChIKey=NXJPNXXZACXFCR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768559   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 768559BDBM768559(tert-butyl N-{2-[(4S,5S)-4- (4-fluorophenyl)-3-met...)
Affinity DataEC50: >1.36E+4nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
12/17/2025
Entry Details
US Patent