BDBM768800 [4-[2-[(2S,3R)-3-fluoro-2-methyl-azetidin-1-yl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]phenyl]methanamine::US12410160, Example 201

SMILES C[C@H]1[C@H](F)CN1c1nc2c(c(-c3ccc(CN)cc3)n1)CCC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 768800   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM768800([4-[2-[(2S,3R)-3-fluoro-2-methyl-azetidin-1-yl]-6,...)
Affinity DataIC50: 1.70nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM768800([4-[2-[(2S,3R)-3-fluoro-2-methyl-azetidin-1-yl]-6,...)
Affinity DataIC50: 2.90nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent